Robert Terkeltaub Selected Research

Febuxostat

7/2022	Superiority of Low-Dose Benzbromarone to Low-Dose Febuxostat in a Prospective, Randomized Comparative Effectiveness Trial in Gout Patients With Renal Uric Acid Underexcretion.
3/2022	Comparative Effectiveness of Allopurinol and Febuxostat in Gout Management.
1/2022	Rationale, design, demographics and baseline characteristics of the randomized, controlled, Phase 2b SAPPHIRE study of verinurad plus allopurinol in patients with chronic kidney disease and hyperuricaemia.
1/2021	Effect of Intensive Urate Lowering With Combined Verinurad and Febuxostat on Albuminuria in Patients With Type 2 Diabetes: A Randomized Trial.
1/2019	Efficacy and safety during extended treatment of lesinurad in combination with febuxostat in patients with tophaceous gout: CRYSTAL extension study.
11/2018	New Perspectives in Rheumatology: Implications of the Cardiovascular Safety of Febuxostat and Allopurinol in Patients With Gout and Cardiovascular Morbidities Trial and the Associated Food and Drug Administration Public Safety Alert.
1/2017	Lesinurad, a Selective Uric Acid Reabsorption Inhibitor, in Combination With Febuxostat in Patients With Tophaceous Gout: Findings of a Phase III Clinical Trial.
1/2010	Update on gout: new therapeutic strategies and options.
4/2009	A critical reappraisal of allopurinol dosing, safety, and efficacy for hyperuricemia in gout.

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.

Realize the full power of the drug-disease research graph!

Robert Terkeltaub Research Topics

Disease

45	Gout 11/2022 - 09/2005
24	Inflammation (Inflammations) 01/2022 - 02/2002
16	Hyperuricemia 07/2022 - 06/2004
9	Osteoarthritis 01/2020 - 06/2005
7	Arthritis (Polyarthritis) 01/2020 - 12/2012
6	Chronic Renal Insufficiency 03/2022 - 01/2009
6	Gouty Arthritis 11/2019 - 01/2006
6	Hypertrophy 07/2010 - 10/2003
6	Hypophosphatasia 06/2008 - 07/2002
5	Chondrocalcinosis (Pseudogout) 10/2017 - 06/2002
4	Joint Diseases (Joint Disease) 01/2018 - 06/2003
3	Pain (Aches) 01/2021 - 01/2016
3	Hyperplasia 01/2019 - 01/2012
3	Arterial calcification of infancy 04/2014 - 01/2005
3	Atherosclerosis 04/2014 - 01/2011
2	Cardiovascular Diseases (Cardiovascular Disease) 01/2022 - 02/2009
2	Neoplasms (Cancer) 01/2022 - 09/2002
2	Hypertension (High Blood Pressure) 01/2022 - 06/2004
2	Albuminuria 01/2022 - 01/2021
2	Type 2 Diabetes Mellitus (MODY) 01/2022 - 01/2021
2	Synovitis 01/2020 - 01/2018
2	Hypersensitivity (Allergy) 10/2016 - 04/2009
2	Knee Osteoarthritis 01/2013 - 04/2004
2	Neointima 06/2012 - 01/2012
2	Atherosclerotic Plaque (Atheroma) 01/2011 - 02/2009
2	Osteomalacia 06/2008 - 06/2005
2	Calcinosis 01/2005 - 06/2003
1	Crystal Arthropathies 10/2022
1	Urolithiasis 07/2022
1	COVID-19 01/2022
1	Myotoxicity 01/2022
1	Liver Diseases (Liver Disease) 01/2022
1	Sepsis (Septicemia) 01/2022
1	Kidney Diseases (Kidney Disease) 01/2022
1	Nephrolithiasis 01/2022
1	Cytopenia 01/2022
1	Cysts 01/2022
1	Dysbiosis 01/2022

Drug/Important Bio-Agent (IBA)

44	Uric Acid (Urate)IBA 11/2022 - 04/2005
12	Allopurinol (Remid)FDA LinkGeneric 03/2022 - 02/2006
9	Febuxostat FDA Link 07/2022 - 04/2009
7	Colchicine FDA LinkGeneric 01/2022 - 06/2005
6	Calcium PyrophosphateIBA 10/2022 - 06/2003
5	lesinuradIBA 01/2019 - 10/2016
5	LigandsIBA 06/2012 - 10/2003
5	diphosphoric acid (pyrophosphoric acid)IBA 03/2005 - 07/2002
4	Xanthine OxidaseIBA 07/2022 - 01/2019
4	InflammasomesIBA 01/2022 - 06/2015
4	AMP-Activated Protein KinasesIBA 01/2020 - 11/2014
4	Urate Oxidase (Uricase)IBA 01/2020 - 10/2007
4	Interleukin-1 (Interleukin 1)IBA 01/2019 - 01/2010
4	Alkaline PhosphataseIBA 06/2008 - 10/2003
4	Durapatite (Hydroxylapatite)IBA 09/2006 - 06/2003
3	Biological ProductsIBA 01/2022 - 01/2006
3	Protein Glutamine gamma Glutamyltransferase 2IBA 01/2019 - 10/2006
3	Pharmaceutical PreparationsIBA 10/2016 - 04/2009
3	OsteopontinIBA 11/2011 - 06/2003
3	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 07/2011 - 12/2005
3	p38 Mitogen-Activated Protein KinasesIBA 06/2008 - 10/2003
3	ChemokinesIBA 01/2006 - 10/2003
3	nucleotide pyrophosphataseIBA 06/2005 - 04/2004
3	Phosphoric Diester Hydrolases (Phosphodiesterases)IBA 06/2005 - 04/2004
2	BenzbromaroneIBA 07/2022 - 10/2016
2	verinuradIBA 01/2022 - 01/2021
2	VaccinesIBA 01/2022 - 11/2019
2	purineIBA 01/2022 - 01/2019
2	CreatinineIBA 01/2022 - 02/2006
2	Interleukin 1 Receptor Antagonist Protein (Anakinra)FDA Link 01/2021 - 01/2019
2	Phosphotransferases (Kinase)IBA 01/2020 - 06/2012
2	DiureticsIBA 01/2019 - 01/2017
2	rilonacept FDA Link 10/2012 - 03/2012
2	aggrecanaseIBA 04/2009 - 06/2008
2	Pattern Recognition ReceptorsIBA 04/2009 - 11/2006
2	Receptor for Advanced Glycation End ProductsIBA 04/2009 - 12/2005
2	Phosphates (Orthophosphate)IBA 12/2008 - 01/2005
2	N- (4'- fluorobutyrophenone)- 4- (4- chlorophenyl)pyridinium (HPP(+))IBA 06/2008 - 09/2007
2	IsoenzymesIBA 06/2008 - 06/2003
2	CytokinesIBA 01/2006 - 02/2002
2	Toll-Like Receptors (Toll-Like Receptor)IBA 01/2006 - 09/2005
2	Collagen Type XIBA 12/2005 - 10/2003
2	CalciumIBA 06/2005 - 06/2003
2	Interleukin-8 (Interleukin 8)IBA 01/2005 - 10/2003
2	TransglutaminasesIBA 10/2003 - 06/2003
2	EnzymesIBA 10/2003 - 06/2003
1	Transaminases (Aminotransferases)IBA 07/2022
1	CholesterolIBA 01/2022
1	COVID-19 VaccinesIBA 01/2022
1	Blood Glucose (Blood Sugar)IBA 01/2022
1	Amino Acids FDA Link 01/2022
1	Aluminum Oxide (Sapphire)IBA 01/2022
1	Phosphoribosyl PyrophosphateIBA 01/2022
1	GuanosineIBA 01/2022
1	AlbuminsIBA 01/2022
1	NucleotidesIBA 01/2022
1	Arginine (L-Arginine)FDA Link 01/2021
1	AntibodiesIBA 01/2021
1	Triamcinolone (Aristocort)FDA Link 01/2021
1	Biomarkers (Surrogate Marker)IBA 01/2021

Therapy/Procedure

24	Therapeutics 11/2022 - 01/2006
3	Ligation 01/2019 - 01/2012